17α-Hydroxyprogesterone CAS 68-96-2

Kev Taw Qhia 17 α- Hydroxyprogesterone, qee zaum hu ua Hydroxyprogesterone (Lus Askiv: hydroxyprogesterone, OHP), yog ib qho endogenous progesterone steroid zoo ib yam li progesterone, thiab kuj yog qhov ua ntej ntawm biosynthesis ntawm ntau cov tshuaj hormones endogenous steroid, suav nrog androgen, estrogen, glucocorticoid, mineralocorticoid thiab qee cov neurosteroids. Bioactive 17-Hydroxyprogesterone (17-OHP) yog ib qho endogenous progesterone thiab ib qho tshuaj intermediate hauv biosynthesis ntawm lwm cov tshuaj hormones steroid. Kev tshawb fawb hauv vitro 17 α- OHP yog ib qho progesterone zoo li chemobookin receptor agonist, txawm hais tias nws cov nyhuv tsis muaj zog. Nws kuj yog ib qho tshuaj intermediate hauv biosynthesis ntawm cov tshuaj hormones steroid xws li androgens, estrogen, cov tshuaj hormones poj niam txiv neej, glucocorticoids, thiab mineralocorticoids. Kev tshawb fawb hauv vivo 17 Hydroxyprogesterone yog ib qho tshuaj steroid inducer zoo rau GVBD (reproductive vesicle rupture). Cov khoom siv tshuaj crystallization (acetone / hexane). Qhov chaw yaj 221 ℃ (219-220 ℃). [α] 20 / D + 97 ° (chlorofor