Sodium triacetoxyborohydride hmoov CAS 56553-60-7

Kev nyab xeeb shipping txoj kev CAS 56553-60-7 hmoov Sodium triacetoxyborohydride
Khoom npe: Sodium triacetoxyborohydride
CAS: 56553-60-7 Nr
Cov mis mos molecular: C6H10BNaO6
Qhov tsos: dawb hmoov
Cov ntsiab lus: 95.0% ~ 105.0% (titration)
Siv: Rau amination txo cov tshuaj tiv thaiv ntawm ketone thiab aldehyde, reductive amination los yog lactamization ntawm carbonyl compound thiab amine, thiab reductive amination ntawm aryl aldehyde
Peev xwm: 5 ~ 10mt / hli

Sodium triacetoxyborohydride (STAB) CAS 56553-60-7 tseem hu ua sodium triacetoxyhydroborate, feem ntau hu ua STAB, yog cov tshuaj sib xyaw nrog cov mis Na (CH3COO) 3BH.Zoo li lwm yam borohydrides, nws yog siv los ua tus neeg sawv cev txo qis hauv cov organic synthesis.Cov ntsev tsis muaj kob no yog npaj los ntawm protonolysis ntawm sodium borohydride nrog acetic acid: NaBH4 + 3 HO2CCH3 → NaBH (O2CCH3) 3 + 3 H2.

Vim muaj cov teebmeem steric thiab hluav taws xob ntawm cov pab pawg acetoxy, sodium triacetoxyborohydride yog ib qho tshuaj txo qis dua li sodium borohydride lossis txawm tias sodium cyanoborohydride.Tsis tas li ntawd, NaBH (OAc) 3 zam cov tshuaj lom neeg sab nrauv tsim los ntawm sodium cyanoborohydride.Sodium triacetoxyborohydride yog tshwj xeeb tshaj yog haum rau reductive aminations ntawm aldehydes thiab ketones.

Txawm li cas los xij, tsis zoo li sodium cyanoborohydride, triacetoxyborohydride yog dej-rhiab heev, thiab dej tsis tuaj yeem siv los ua cov kuab tshuaj nrog cov tshuaj no, thiab nws tsis haum rau methanol.Nws reacts qeeb qeeb nrog ethanol thiab isopropanol thiab tuaj yeem siv nrog cov no.NaBH (OAc)3 kuj tseem siv tau rau kev txo qis alkylation ntawm cov amines theem nrab nrog aldehyde-bisulfite adducts.