Koj puas ua haujlwm hauv kev tshawb fawb biomedical? Yog tias muaj, ces koj yuav tau hnov ntawm Sulfo-NHS. Raws li lub luag haujlwm tseem ceeb ntawm cov compound no nyob rau hauv kev tshawb fawb txuas ntxiv tau lees paub, qhov no compound tau nkag ntau lub chaw soj ntsuam thoob ntiaj teb. Hauv tsab xov xwm no, peb tham txog dab tsi Sulfo-NHS yog thiab vim li cas nws yog xws li cov cuab yeej tseem ceeb rau cov kev kawm txog biological sciences.
Ua ntej, dab tsi yog Sulfo-NHS? Lub npe yog lub ntev ntev-wared, yog li cia peb ua kom nws poob. Sulfo sawv rau sulfonic acid thiab NHS sawv rau n-hydroxysuccinimide. Thaum ob lub tebchaw sib xyaw ua ke,Sulfo-NHSyog tsim tawm. Qhov no compound muaj ob peb siv nyob rau hauv biomedical kev tshawb fawb, tab sis ib qho ntawm nws cov khoom tseem ceeb yog lub peev xwm los xaiv cov khoom siv cov khoom pov tseg.
Sulfo-NHS ua haujlwm los ntawm kev rov ua haujlwm nrog thawj lub npe nyiaj (piv txwv li -NH2 pawg) ntawm sab saw ntawm lysine seem nyob rau hauv cov protein. Qhov tseem ceeb, sulfo-nth Qhov no tau ua rau ntau qhov chaw ntawm kev tshawb fawb tau mus tom ntej nrog cov raug thiab ntau dua cov ncauj lus nthuav dav.
Yog li, dab tsi yog sulfo-nhs siv rau? Ib qho kev siv ntawm cov compound no yog nyob rau hauv kev tshawb fawb txhaj tshuaj. Sulfo-NHS tau pom tias cov tub rog tau pom zoo thiab antigens, qhib cov hom kev tshiab rau kev kawm tsis muaj zog ntawm cov kab mob thiab kab mob. Tsis tas li ntawd,Sulfo-NHSYuav siv tau nyob rau hauv cov protein-protein kev sib txuam kev tshawb fawb raws li nws tso cai cov kws tshawb nrhiav kom nrawm nrawm thiab pom tau yooj yim thaum muaj ob qhov protein cuam tshuam.
Lwm qhov chaw uas Sulfo-NHS yog siv dav dav yog qhov proteomics. Cov proteomics kawm cov qauv thiab kev ua ntawm txhua cov protein hauv kev muaj sia, thiabSulfo-NHSyog cov cuab yeej tseem ceeb hauv kev txheeb xyuas no. Los ntawm tagging cov protein nrog Sulfo-NHS tuaj yeem ua cov kev sim kom tau txais cov ntaub ntawv ntxaws ntxaws txog kev muab cov khoom muaj txiaj ntsig ntxiv txog kev muab cov khoom muaj txiaj ntsig zoo ntxiv txog kev muab cov khoom muaj txiaj ntsig zoo ntxiv txog kev muab cov khoom muaj txiaj ntsig ntxiv txog kev muab cov khoom muaj txiaj ntsig zoo ntxiv txog kev muab cov khoom muaj txiaj ntsig zoo ntxiv txog kev muab cov khoom muaj txiaj ntsig zoo ntxiv txog kev muab cov khoom muaj txiaj ntsig zoo ntxiv txog cov peev txheej biomarkers rau kab mob.
Sulfo-NHS tseem ua lub luag haujlwm hauv kev txhim kho cov tshuaj tshiab. Thaum cov kws tshawb nrhiav tab tom sim tsim cov tshuaj tshiab, nws yog ib qho tseem ceeb kom nws ua tau cov protein thiab tsis muaj lwm cov protein hauv lub cev. Los ntawm kev sivSulfo-NHSTxhawm rau xaiv cov tshuaj tiv thaiv, cov kws tshawb nrhiav tuaj yeem txheeb xyuas cov hom phiaj ntawm cov tshuaj muaj peev xwm ua kom sai li cas cov tshuaj txhim kho.
Yog li ntawd koj muaj nws! Sulfo-NHS tej zaum yuav tsis yog ib lub sijhawm paub nyob sab nraud ntawm lub zej zog scientific, tab sis cov compound no tau nrawm dhau los ua ib qho cuab yeej muaj txiaj ntsig hauv biomedical kev tshawb fawb. Los ntawm kev tshawb fawb txhaj tshuaj rau cov proteomics rau kev tsim kho yeeb tshuaj los rau cov kws tshawb fawb ua cov kev nce qib loj hauv cov ntawv pom zoo no tom ntej no.
Lub sij hawm Post: Jun-12-2023