17a-Hydroxyprogesterone CAS 68-96-2

Taw qhia 17 α- Hydroxyprogesterone, qee zaum hu ua Hydroxyprogesterone (Lus Askiv: hydroxyprogesterone, OHP), yog ib qho endogenous progesterone steroid zoo ib yam li progesterone, thiab tseem yog tus thawj coj ntawm biosynthesis ntawm ntau cov tshuaj hormones endogenous steroid, suav nrog androgen, estrogen, glucoticcorticosteroids. qee cov neurosteroids.Bioactive 17-Hydroxyprogesterone (17-OHP) yog ib qho endogenous progesterone thiab cov tshuaj nruab nrab hauv biosynthesis ntawm lwm cov tshuaj steroid.Hauv vitro kev tshawb fawb 17 α- OHP yog ib qho progesterone zoo li chemobookin receptor agonist, txawm hais tias nws cov nyhuv tsis muaj zog.Nws kuj yog ib qho tshuaj nruab nrab hauv biosynthesis ntawm cov tshuaj steroid xws li androgens, estrogen, poj niam txiv neej cov tshuaj hormones, glucocorticoids, thiab mineralocorticoids.Hauv vivo txoj kev tshawb fawb 17 Hydroxyprogesterone yog ib qho zoo steroid inducer rau GVBD (kev ua me nyuam vesicle rupture).Cov khoom siv tshuaj crystallization (acetone / hexane).Melting point 221 ℃ (219-220 ℃).[ α] 20 / D + 97 ° (chlorofor